AEBP2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66141-1-Ig |CloneNo.: 7H2B11

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Freight/Packing

Con: 140 μg/150μl

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Tested Applications

Applications:
ELISA, WB
Application not tested? Please see our Guarantee




Species specificity:
human, pig

Positive WB detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:5000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
AE binding protein 2

Calculated molecular weight:
33 kDa,54 kDa

Observed molecular weight:
55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AEBP2

Synonyms
AE binding protein 2, AEBP2, Zinc finger protein AEBP2
Background

AEBP2 belongs to the AEBP2/jing C2H2-type zinc-finger family. It is a DNA-binding transcriptional repressor. AEBP2 is a zinc finger protein that has been shown to interact with the mammalian Polycomb Repression Complex 2 (PRC2). It may interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. AEBP2 is an evolutionarily well-conserved gene that is found in the animals ranging from flying insects to mammals. (PMID:19293275) The antibody recognizes adult-specific larger form (52 kDa) and the embryo-specific smaller form (31 kDa).


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