ADH1C Recombinant antibody, PBS Only

ADH1C Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241623A3

Cat no : 84546-2-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 84546-2-RR (same clone as 84546-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84546-2-RR (ADH1C antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84546-2-PBS in a different storage buffer formulation.

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Product Information

The immunogen of 84546-2-PBS is ADH1C Fusion Protein expressed in E. coli.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: ADH1C fusion protein Ag13528
• Full Name: alcohol dehydrogenase 1C (class I), gamma polypeptide
• Calculated Molecular Weight: 375 aa, 40 kDa
• Observed Molecular Weight: 37-45 kDa
• GenBank Accession Number: BC062476
• Gene Symbol: ADH1C
• Gene ID (NCBI): 126
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Alcohol dehydrogenase 1C(ADH1C), also known as ADH3, is an alcohol dehydrogenase that can catalyze ethanol oxidation to metabolite acetaldehyde. According to THE HUMAN PROTEIN ATLAS database, ADH1C locates mainly to the cytosol and plasma membrane. Genetic polymorphism of the ADH1C gene (ADH1C*1 allele) is associated with various human cancers, such as gastric cancer, oral cancer and CRC, for it encodes an alcohol dehydrogenase producing 2.5 times more acetaldehyde.(PMID: 35300114)