ACAP3 Polyclonal antibody, PBS Only

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  WB analysis of Jurkat using 17570-1-AP (same clone as 17570-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 17570-1-AP (ACAP3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17570-1-PBS in a different storage buffer formulation.

• 

  WB analysis of SH-SY5Y using 17570-1-AP (same clone as 17570-1-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 17570-1-AP (ACAP3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17570-1-PBS in a different storage buffer formulation.

• 

  IF Staining of SH-SY5Y using 17570-1-AP (same clone as 17570-1-PBS)

  Immunofluorescent analysis of (10% Formaldehyde) fixed SH-SY5Y cells using 17570-1-AP (ACAP3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 17570-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

ACAP3 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 17570-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

KIAA1716, Cnt-b5, CENTB5, Centaurin-beta-5, Centaurin beta 5

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Product Information

17570-1-PBS targets ACAP3 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: ACAP3 fusion protein Ag11777
• Full Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
• Calculated Molecular Weight: 834 aa, 92 kDa
• Observed Molecular Weight: 85kda, 92 kDa
• GenBank Accession Number: BC047001
• Gene Symbol: ACAP3
• Gene ID (NCBI): 116983
• RRID: AB_2257668
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q96P50
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

ACAP3 (Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3) , also known as CENTB5, is a protein-coding gene that belongs to the ACAP family of GTPase-activating proteins (GAPs). ACAP3 is involved in neuronal migration in the developing cerebral cortex of mice. Knockdown of ACAP3 in the developing cortical neurons of mice in utero significantly abrogated neuronal migration in the cortical layer, ACAP3 is involved in neuronal migration in the developing cerebral cortex of mice. Knockdown of ACAP3 in the developing cortical neurons of mice in utero significantly abrogated neuronal migration in the cortical layer (PMID: 28919417),