14-3-3 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66061-1-Ig |CloneNo.: 2E10A3

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Freight/Packing

Con: 107 μg/150 μl

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Species specificity:
human, rat

Positive WB detected in:
human brain tissue, HeLa cells, HepG2 cells

Positive IHC detected in:
human lung cancer tissue, human lung cancer tissue, rat brain tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:5000
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

Calculated molecular weight:
28 kDa

Observed molecular weight:
31 kDa,28 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
YWHAQ

Synonyms
14 3 3, 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 14-3-3 tau, HS1, Protein HS1, YWHAQ
Background

14-3-3 proteins interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. 66061-1-Ig recognizes 14-3-3 tau (YWHAQ), eta (YWHAH), and zeta (YWHAZ), but not epsilon (YWHAE).


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