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Anti-Human IFNAR1 Rabbit Recombinant Antibody

IFNAR1 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

230549B1

Cat no : 98067-1-RR

Synonyms

IFN alpha REC, Cytokine receptor class-II member 1, CRF2-1, CRF2 1, AVP

Validation Data Gallery

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  • Flow cytometry (FC) experiment of U-937 cells using Anti-Human IFNAR1 Rabbit Recombinant Antibody (98067-1-RR)

    FC experiment of U-937 using 98067-1-RR

    1x10^6 U-937 cells were surface stained with 0.25 ug Anti-Human IFNAR1 Rabbit Recombinant Antibody (98067-1-RR, Clone:230549B1) and PE-Conjugated Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were not fixed.

  • Affinity and Kinetic Characterization of 98067-1-RR

    Affinity and Kinetic Characterization of 98067-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98067-1-RR against Human IFNAR1 were performed. The affinity constant is 1.15 nM.

Tested Applications

Positive FC detected inU-937 cells

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 98067-1-RR is IFNAR1 Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Fusion Protein
Full Name interferon (alpha, beta and omega) receptor 1
Calculated Molecular Weight 557 aa, 64 kDa
GenBank Accession NumberBC021825
Gene Symbol IFNAR1
Gene ID (NCBI) 3454
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

Background Information

Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.

Protocols

Product Specific Protocols
FC protocol for IFNAR1 antibody 98067-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols