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Anticorps Polyclonal de lapin anti-Adiponectin receptor

Adiponectin receptor Polyclonal Antibody for WB, IP, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris et plus (2)

Applications

WB, IP, IF, IHC, ELISA

Conjugaison

Non conjugué

N° de cat : 14361-1-AP

Synonymes

ACDCR2, adiponectin receptor 2, Adiponectin receptor protein 2, ADIPOR1, ADIPOR2, PAQR2



Applications testées

Résultats positifs en WBcellules HeLa, cellules A549, cellules L02, tissu hépatique de rat, tissu placentaire humain
Résultats positifs en IPtissu hépatique de souris,

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunoprécipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

14361-1-AP cible Adiponectin receptor dans les applications de WB, IP, IF, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Réactivité citéerat, Humain, porc, souris, Hamster
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Adiponectin receptor Protéine recombinante Ag5744
Nom complet adiponectin receptor 2
Masse moléculaire calculée 44 kDa
Poids moléculaire observé 40-45 kDa
Numéro d’acquisition GenBankBC051858
Symbole du gène Adiponectin receptor
Identification du gène (NCBI) 79602
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin (ADIPOR1 and ADIPOR2) have been identified. They mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. The human ADIPOR2 gene maps to chromosome 12p13.31, and encodes a 386-amino acid protein with a molecular weight of 44 kDa. This antibody raised against 1-147aa of human AdipoR2 may cross-react with AdipoR1.

Protocole

Product Specific Protocols
WB protocol for Adiponectin receptor antibody 14361-1-APDownload protocol
IP protocol for Adiponectin receptor antibody 14361-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIF

Redox Biol

Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction.

Authors - Yuan Liu
hamsterWB

Cancer Sci

Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.

Authors - Haoyi Jin
mouseWB

Food Funct

Quercetin regulates skeletal muscle fiber type switching via adiponectin signaling.

Authors - Xiaoling Chen
mouseWB

Food Funct

D-chiro-Inositol facilitates adiponectin biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition.

Authors - Qiong Yang
ratWB,IF

J Alzheimers Dis

Advanced Glycosylation End Products Induced Synaptic Deficits and Cognitive Decline Through ROS-JNK-p53/miR-34c/SYT1 Axis in Diabetic Encephalopathy

Authors - Rui Zhang
mouseWB

Gene

The Mef2c/AdipoR1 axis is responsible for myogenic differentiation and is regulated by resistin in skeletal muscles

Authors - Fengyun Wen