- Phare
- Validé par KD/KO
Anticorps Polyclonal de lapin anti-Adiponectin receptor
Adiponectin receptor Polyclonal Antibody for WB, IP, ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, rat, souris et plus (2)
Applications
WB, IP, IF, IHC, ELISA
Conjugaison
Non conjugué
N° de cat : 14361-1-AP
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en WB | cellules HeLa, cellules A549, cellules L02, tissu hépatique de rat, tissu placentaire humain |
Résultats positifs en IP | tissu hépatique de souris, |
Dilution recommandée
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:2000 |
Immunoprécipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Applications publiées
KD/KO | See 2 publications below |
WB | See 17 publications below |
IHC | See 2 publications below |
IF | See 3 publications below |
IP | See 1 publications below |
Informations sur le produit
14361-1-AP cible Adiponectin receptor dans les applications de WB, IP, IF, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris
Réactivité | Humain, rat, souris |
Réactivité citée | rat, Humain, porc, souris, Hamster |
Hôte / Isotype | Lapin / IgG |
Clonalité | Polyclonal |
Type | Anticorps |
Immunogène | Adiponectin receptor Protéine recombinante Ag5744 |
Nom complet | adiponectin receptor 2 |
Masse moléculaire calculée | 44 kDa |
Poids moléculaire observé | 40-45 kDa |
Numéro d’acquisition GenBank | BC051858 |
Symbole du gène | Adiponectin receptor |
Identification du gène (NCBI) | 79602 |
Conjugaison | Non conjugué |
Forme | Liquide |
Méthode de purification | Purification par affinité contre l'antigène |
Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin (ADIPOR1 and ADIPOR2) have been identified. They mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. The human ADIPOR2 gene maps to chromosome 12p13.31, and encodes a 386-amino acid protein with a molecular weight of 44 kDa. This antibody raised against 1-147aa of human AdipoR2 may cross-react with AdipoR1.
Protocole
Product Specific Protocols | |
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WB protocol for Adiponectin receptor antibody 14361-1-AP | Download protocol |
IP protocol for Adiponectin receptor antibody 14361-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Redox Biol Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction. | ||
Cancer Sci Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer. | ||
Food Funct Quercetin regulates skeletal muscle fiber type switching via adiponectin signaling. | ||
Food Funct D-chiro-Inositol facilitates adiponectin biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition. | ||
J Alzheimers Dis Advanced Glycosylation End Products Induced Synaptic Deficits and Cognitive Decline Through ROS-JNK-p53/miR-34c/SYT1 Axis in Diabetic Encephalopathy | ||
Gene The Mef2c/AdipoR1 axis is responsible for myogenic differentiation and is regulated by resistin in skeletal muscles |