ADIPOQ Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66239-1-Ig |CloneNo.: 5D8A7

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Freight/Packing

Con: 134 μg/150μl

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Species specificity:
human

Positive WB detected in:
human adipose tissue

Recommended dilution:
WB : 1:500-1:5000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. 20uL sizes contain 0.05% BSA. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
adiponectin, C1Q and collagen domain containing

Calculated molecular weight:
244aa,26 kDa

Observed molecular weight:
29 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADIPOQ

Synonyms
ACDC, ACRP30, adiponectin, ADIPOQ, ADIPQTL1, ADPN, APM 1, APM1, GBP28, Gelatin binding protein
Background

Adiponectin (AdipoQ), an adipocyte-derived hormone, is one of the most abundant adipokines in the blood circulation. Adiponectin modulates a number of metabolic processes, including improving insulin sensitivity and anti-inflammatory activity. The role of AdipoQ in reproduction is not yet fully understood, but the expression of AdipoQ in reproductive tissues has been observed in various animals and humans, including chicken testis, bovine ovary, and human placenta. Adiponectin exerts its effects by activating a range of different signaling molecules via binding to two transmembrane AdipoQ receptors, AdipoR1 and AdipoR2. AdipoR1 is expressed primarily in the skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. AdipoQ May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors.


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