LAMP2 Polyklonaler Antikörper

LAMP2 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (2)

Anwendung

IF, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen

20

Kat-Nr. : 10397-1-AP

Synonyme

CD107b, LAMP 2, LAMP2, LAMPB, LGP110

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Galerie der Validierungsdaten

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  IHC staining of human pancreas cancer using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 10397-1-AP (LAMP2 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human pancreas cancer using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 10397-1-AP (LAMP2 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human placenta using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta using 10397-1-AP (LAMP2 antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human placenta using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta using 10397-1-AP (LAMP2 antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human skeletal muscle using 10397-1-AP

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle using 10397-1-AP (LAMP2 antibody) at dilution of 1:50 (under 40x lens).

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  IF Staining of HepG2 using 10397-1-AP

  Immunofluorescent analysis of HepG2 cells, using LAMP2 antibody 10397-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

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  IF Staining of HepG2 using 10397-1-AP

  Immunofluorescent analysis of HepG2 cells, using LAMP2 antibody 10397-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

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Geprüfte Anwendungen

Veröffentlichte Anwendungen

• IHC: See 4 publications below
• IF: See 7 publications below

Produktinformation

10397-1-AP bindet in IF, IHC, ELISA LAMP2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: LAMP2 fusion protein Ag0595
• Vollständiger Name: lysosomal-associated membrane protein 2
• Berechnetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: BC002965
• Gene symbol: LAMP2
• Gene ID (NCBI): 3920
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides, with apparent molecular weight ranging from 45-130 kDa.

Publikationen

Species	Application	Title
human	IF	Oxid Med Cell Longev; The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease.; Authors - Jinhua Wu
human		Cell Death Dis; Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.; Authors - L Zhang
human	IF	Acta Neuropathol Commun; Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.; Authors - Petra Frick
mouse	IF	Sci Rep; Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.; Authors - Takeshi Into
mouse		Biomedicines; IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3.; Authors - Yong-Shiou Lin
mouse	IF	Front Pharmacol; Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy.; Authors - Jiao Zhou

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