Chemical compound 5-methylcytosine Monoclonal antibody, PBS Only

5-methylcytosine Monoclonal Antibody for IHC, Dot Blot, ELISA, Indirect ELISA
Cat No. 68301-1-PBS
Clone No.2C9G9

Host / Isotype

Mouse / IgG2b

Reactivity

5mc, chemical compound, m5c

Applications

IHC, Dot Blot, ELISA, Indirect ELISA

m5C, RNA methylation, 5mC

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

68301-1-PBS targets 5-methylcytosine in IHC, Dot Blot, ELISA, Indirect ELISA applications and shows reactivity with 5mc, chemical compound, m5c samples.

Tested Reactivity 5mc, chemical compound, m5c
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen Compound Predict reactive species
Full Name 5-methylcytosine
Gene Symbol
Gene ID (NCBI)
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

In eukaryotes, 5-methylcytosine in DNA (5mC) and its oxidized derivatives (5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC)) are the most prominent modifications and have been suggested to contribute to epigenetic gene regulation through a variety of different mechanisms. m5C has also been found in mRNA, rRNA and tRNA of representative organisms from all kinds of species. As reversible epigenetic modifications, m5C modifications of RNA affect the fate of the modified RNA molecules and play important roles in various biological processes including RNA stability control, protein synthesis, and transcriptional regulation (PMID: 35365216). This antibody can recognize both 5mC in DNA and m5C in RNA.

Protocol for Dot Blot:
https://www.ptglab.com/protocol/68301-1-IgDotBlot.pdf

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