Beta-galactosidase: An essential enzyme
Beta-galactosidase, also known as beta-Gal or GLB1, is an essential enzyme that hydrolyzes beta-galactosides into monosaccharides. It cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
|Beta-galactosidase||Rabbit polyclonal||15518-1-AP||ELISA, WB, IF||3|
|Immunofluorescent analysis of Hela cells using GLB1 antibody at 1.25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).||SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 15518-1-AP(GLB1 antibody) at dilution of 1:400|
GLB1 (Beta-galactosidase) is also named as ELNR1, Lactase.It cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.This protein is identical to the elastin-binding protein (EBP), a major component of the nonintegrin cell surface receptor complex expressed in fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types.Defects in GLB1 are the cause of GM1-gangliosidosis type 1 (GM1G1) ,GM1-gangliosidosis type 2 (GM1G2),GM1-gangliosidosis type 3 (GM1G3) and mucopolysaccharidosis type 4B (MPS4B).