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ChromoTek anti-IFNy recombinant VHH, for NHS conjugation

IFNgNHS is an unconjugated recombinant anti IFNg Nanobody (VHH). Suitable for for NHS conjugation.

Host/Type

Alpaca VHH

Reactivity

Human

Applications

Conjugation

Conjugate

Unconjugated

Cat no : IFNgNHS

Synonyms

IFNg VHH, IFNg single domain antibody (sdAb), Interferon Gamma, Immune interferon, Interferon

Validation Data Gallery

  • BLI analysis of the interaction between varying concentrations of anti-IFNg VHH (IFNgNHS) and immobilised, biotinylated HumanKine Interferon γ (HZ-1301). Fit indicates fitting of data to a 1:1 binding model.

    BLI analysis of the interaction between varying concentrations of anti-IFNg VHH (IFNgNHS) and immobilised, biotinylated HumanKine Interferon γ (HZ-1301). Fit indicates fitting of data to a 1:1 binding model.

Product Information

IFNgNHS is an unconjugated recombinant anti IFNg Nanobody (VHH). Suitable for for NHS conjugation.

ApplicationsConjugation
ReactivityHuman
ConjugateUnconjugated
TypeNanobody
ClassRecombinant
HostAlpaca
AffinityPicomolar range, below the assay limit (biolayer interferometry)
Molecular Weight14.4 kDa
FormLiquid
RRIDAB_3665971
Storage Buffer10 mM HEPES pH 7.0, 500 mM NaCl, 0.09% sodium azide
Storage ConditionStore at -20°C
Shippingdry ice
BackgroundIFN gamma (IFNG) is a soluble cytokine that is the only member of the type II class of IFN. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB).