ChromoTek anti-IFNy recombinant VHH, biotinylated

IFNg-b is a recombinant mono-biotinylated anti IFNg Nanobody (VHH), suitable for ELISA, SPR, and BLI applications.

Host/Type

Alpaca VHH

Reactivity

Human

Applications

BLI, SPR, ELISA

Conjugate

Biotin

Cat no : IFNg-b

Synonyms

IFNg VHH, IFNg single domain antibody (sdAb), Interferon Gamma, Immune interferon, Interferon

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Validation Data Gallery

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  BLI analysis of the capture of varying concentrations of HumanKine Interferon γ (HZ-1301) by biotinylated anti-INFg VHH (IFNgNHS).

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  ELISA analysis of the capture of varying concentrations of HumanKine Interferon γ (HZ-1301) by biotinylated anti-INFg VHH (IFNgNHS). Detection via rabbit polyclonal PTG 15365-1-AP.

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Product Information

IFNg-b is a recombinant mono-biotinylated anti IFNg Nanobody (VHH), suitable for ELISA, SPR, and BLI applications.

• Applications: BLI, SPR, ELISA
• Reactivity: Human
• Conjugate: Biotin
• Type: Nanobody
• Class: Recombinant
• Host: Alpaca
• Affinity: Picomolar range, below the assay limit (biolayer interferometry)
• Molecular Weight: 14.4 kDa
• Form: Liquid
• RRID: AB_3665388
• Storage Buffer: 10 mM HEPES pH 7.0, 500 mM NaCl, 5 mM EDTA, 0.09% sodium azide
• Storage Condition: Store at -20°C
• Shipping: ambient
• Background: IFN gamma (IFNG) is a soluble cytokine that is the only member of the type II class of IFN. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB).