• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

ChromoTek anti-FGF-9 recombinant VHH, biotinylated

fgf9-b is a recombinant mono-biotinylated anti FGF9 Nanobody (VHH), suitable for ELISA, SPR, and BLI applications.

Host/Type

Alpaca VHH

Reactivity

Human

Applications

BLI, SPR, ELISA

Conjugate

Biotin

Cat no : fgf9-b

Synonyms

FGF9-VHH, FGF9 single domain antibody (sdAb), FGF9, FGF-9

Validation Data Gallery

  • BLI analysis of the capture of varying concentrations of HumanKine FGF-9 (HZ-1329) by biotinylated anti-FGF-9 VHH (fgf9-b). Please note the higher apparent affinity owing to avidity effects (dimerization of the cytokine).

    BLI analysis of the capture of varying concentrations of HumanKine FGF-9 (HZ-1329) by biotinylated anti-FGF-9 VHH (fgf9-b). Please note the higher apparent affinity owing to avidity effects (dimerization of the cytokine).

  • ELISA analysis of the capture of varying concentrations of HumanKine FGF-9 (HZ-1329) by biotinylated anti-FGF-9 VHH (fgf9-b). Detection via rabbit polyclonal PTG 26554-1-AP.

    ELISA analysis of the capture of varying concentrations of HumanKine FGF-9 (HZ-1329) by biotinylated anti-FGF-9 VHH (fgf9-b). Detection via rabbit polyclonal PTG 26554-1-AP.

Product Information

fgf9-b is a recombinant mono-biotinylated anti FGF9 Nanobody (VHH), suitable for ELISA, SPR, and BLI applications.

ApplicationsBLI, SPR, ELISA
ReactivityHuman
ConjugateBiotin
TypeNanobody
ClassRecombinant
HostAlpaca
Affinity/
Molecular Weight14.8 kDa
FormLiquid
RRIDAB_3665411
Storage Buffer10 mM HEPES pH 7.0, 500 mM NaCl, 5 mM EDTA, 0.09% sodium azide
Storage ConditionStore at -20°C
Shippingambient
BackgroundFGF-9 is a 26 kdA, glycosylated protein that is a member of the FGF superfamily. It primarily binds with FGFR3 and plays prominent roles in the regulating embryonic, lung, and skeletal development. It is a key regulator of male sex determination through promoting the proliferation of pre-Sertoli cells. It signals in conjunction with FGF-10 and SHH to drive the development of the lung mesenchymal space. FGF-9 is also a positive regulator of chondrocyte proliferation and osteogenesis during the bone formation process. Overexpression of loss of FGF-9 during skeletal development often results in aberrant bone growth. (PMID: 28395336, 25772309, 16540513, 25435023).