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ZMPSTE24 Recombinant antibody, PBS Only

ZMPSTE24 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241288C3

Cat no : 84547-2-PBS

Synonyms

FACE-1, FACE1, FACE 1, EC:3.4.24.84, CAAX prenyl protease 1 homolog

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of PC-3 cells using ZMPSTE24 Recombinant antibody (84547-2-RR)

    IF Staining of PC-3 using 84547-2-RR (same clone as 84547-2-PBS)

    Immunofluorescent analysis of (4% PFA) fixed PC-3 cells using ZMPSTE24 antibody (84547-2-RR, Clone: 241288C3 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84547-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84547-2-RR

    Affinity and Kinetic Characterization of 84547-2-RR

    Biolayer interferometry (BLl) kinetic assays of 84547-2-RR against Human ZMPSTE24 were performed. The affinity constant is below 1 pM.

Product Information

The immunogen of 84547-2-PBS is ZMPSTE24 Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ZMPSTE24 fusion protein Ag33613
Full Name zinc metallopeptidase (STE24 homolog, S. cerevisiae)
Calculated Molecular Weight 475 aa, 55 kDa
GenBank Accession NumberBC037283
Gene Symbol ZMPSTE24
Gene ID (NCBI) 10269
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ZMPSTE24(CAAX prenyl protease 1 homolog) gene encodes a zinc metalloproteinase involved in the processing of farnesylated proteins(PubMed: 10373325). The significance of ZMPSTE24 in human disease stems from its role as an enzyme necessary for the correct processing and maturation of lamin A ,an intermediate filament component of the nuclear envelope (PubMed: 16297189).