Product Information
84902-1-PBS targets XPR1 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | XPR1 fusion protein Ag5373 Predict reactive species |
Full Name | xenotropic and polytropic retrovirus receptor |
Calculated Molecular Weight | 696 aa, 82 kDa |
Observed Molecular Weight | 74 kDa |
GenBank Accession Number | BC041142 |
Gene Symbol | XPR1 |
Gene ID (NCBI) | 9213 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q9UBH6 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
XPR1 is a receptor for xenotropic and polytropic murine leukemia retroviruses and a homolog of yeast Syg1 and plant Pi transporter PHO1 (PMID: 20633538). XPR1 has been identified as an atypical G-protein-coupled receptor. Xenotropic or polytropic retrovirus binding to XPR1 can disrupt the cAMP-mediated signaling function of Xpr1, leading to the apoptosis of infected cells (PMID: 22090134). A band of about 82-100 kDa is probably due to abnormal migration of the protein or post-translation modifications. In addition, a band of about 55-72 kDa may be isoforms and fragments.