XLF Monoclonal antibody, PBS Only

XLF Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F8C7

Cat no : 66552-1-PBS

Synonyms

NHEJ1, Protein cernunnos, XLF, XRCC4 like factor



Product Information

66552-1-PBS targets XLF in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen XLF fusion protein Ag2496
Full Name nonhomologous end-joining factor 1
Calculated Molecular Weight 35 kDa
Observed Molecular Weight 37 kDa
GenBank Accession NumberBC030986
Gene Symbol XLF
Gene ID (NCBI) 79840
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

XRCC4-like factor (XLF), also known as Cernunnos and NHEJ1, is a protein encoded by the human NHEJ1 gene and an important repair factor for DNA double-strand breaks. NHEJ is a well-known mechanism for the repair of double-strand breaks (DSBs), a lethal type of DNA damage in mammalian cells. It basically utilizes a group of enzymes to take hold of the ends of a broken DNA molecule, create a bridge between them, and subsequently re-ligate the broken DNA molecule.