XLF Monoclonal antibody, PBS Only
XLF Monoclonal Antibody for WB, IHC, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human
Applications
WB, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1F8C7
Cat no : 66552-1-PBS
Synonyms
Validation Data Gallery
Product Information
66552-1-PBS targets XLF in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | XLF fusion protein Ag2496 |
Full Name | nonhomologous end-joining factor 1 |
Calculated Molecular Weight | 35 kDa |
Observed Molecular Weight | 37 kDa |
GenBank Accession Number | BC030986 |
Gene Symbol | XLF |
Gene ID (NCBI) | 79840 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
XRCC4-like factor (XLF), also known as Cernunnos and NHEJ1, is a protein encoded by the human NHEJ1 gene and an important repair factor for DNA double-strand breaks. NHEJ is a well-known mechanism for the repair of double-strand breaks (DSBs), a lethal type of DNA damage in mammalian cells. It basically utilizes a group of enzymes to take hold of the ends of a broken DNA molecule, create a bridge between them, and subsequently re-ligate the broken DNA molecule.