XLF Polyclonal antibody, PBS Only

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  WB analysis using 11888-1-AP (same clone as 11888-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11888-1-AP (XLF antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11888-1-PBS in a different storage buffer formulation.

XLF Polyclonal Antibody for WB, Indirect ELISA

Cat No. 11888-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

11888-1-PBS targets XLF in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: XLF fusion protein Ag2496
• Full Name: nonhomologous end-joining factor 1
• Calculated Molecular Weight: 35 kDa
• Observed Molecular Weight: 33-38 kDa
• GenBank Accession Number: BC030986
• Gene Symbol: XLF
• Gene ID (NCBI): 79840
• RRID: AB_2282851
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H9Q4
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

XRCC4-like factor (XLF), also known as Cernunnos and NHEJ1, is a protein encoded by the human NHEJ1 gene and an important repair factor for DNA double-strand breaks. NHEJ is a well-known mechanism for the repair of double-strand breaks (DSBs), a lethal type of DNA damage in mammalian cells. It basically utilizes a group of enzymes to take hold of the ends of a broken DNA molecule, create a bridge between them, and subsequently re-ligate the broken DNA molecule.