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XLF Polyclonal antibody, PBS Only

XLF Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11888-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using XLF Polyclonal antibody (11888-1-AP)

    WB analysis using 11888-1-AP (same clone as 11888-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11888-1-AP (XLF antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11888-1-PBS in a different storage buffer formulation.

Product Information

11888-1-PBS targets XLF in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen XLF fusion protein Ag2496
Full Name nonhomologous end-joining factor 1
Calculated Molecular Weight 35 kDa
Observed Molecular Weight 33-38 kDa
GenBank Accession NumberBC030986
Gene Symbol XLF
Gene ID (NCBI) 79840
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

XRCC4-like factor (XLF), also known as Cernunnos and NHEJ1, is a protein encoded by the human NHEJ1 gene and an important repair factor for DNA double-strand breaks. NHEJ is a well-known mechanism for the repair of double-strand breaks (DSBs), a lethal type of DNA damage in mammalian cells. It basically utilizes a group of enzymes to take hold of the ends of a broken DNA molecule, create a bridge between them, and subsequently re-ligate the broken DNA molecule.