Product Information
22047-1-PBS targets WIPF1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | WIPF1 fusion protein Ag16975 Predict reactive species |
Full Name | WAS/WASL interacting protein family, member 1 |
Calculated Molecular Weight | 403aa,40 kDa; 503aa,51 kDa |
Observed Molecular Weight | 51 kDa |
GenBank Accession Number | BC110288 |
Gene Symbol | WIPF1 |
Gene ID (NCBI) | 7456 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | O43516 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
WASP interacting protein family member 1(WIPF1), also known as WIP, is a ubiquitously expressed proline-rich multidomain protein and plays a role in the reorganization of the actin cytoskeleton. Mutations in the WIPF1 binding site of the Wiskott-Aldrich syndrome protein or in WIPF1 itself cause Wiskott-Aldrich syndrome, which predisposes people to cancer, such as leukemia and lymphoma(PMID: 27863429).