Vpr Polyclonal antibody

• Featured Product
• KD/KO Validated

Vpr Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

immunodeficiency virus 1 and More (2)

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

12

Cat no : 51143-1-AP

Synonyms

Vpr

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Validation Data Gallery

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Published Applications

• KD/KO: See 2 publications below
• WB: See 11 publications below

Product Information

51143-1-AP targets Vpr in WB, ELISA applications and shows reactivity with immunodeficiency virus 1 samples.

• Tested Reactivity: immunodeficiency virus 1
• Cited Reactivity: human, virus
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Vpr fusion protein Ag0718
• Full Name: Vpr
• Calculated Molecular Weight: 11 kDa
• GenBank Accession Number: NP_057852
• RRID: AB_10695191
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

This antibody recognize the VPR gene of Human immunodeficiency virus 1.

Publications

Species	Application	Title
human	WB	Nat Commun; HIV reprograms host m 6 Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1; Authors - Qiong Zhang
human	WB	Proc Natl Acad Sci U S A; CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection.; Authors - Franziska K Geis
	WB	Retrovirology; A functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction.; Authors - Marek Widera ; KO Validated
virus	WB	J Biol Chem; HIV-1 Vpu induces caspase-mediated cleavage of IRF3.; Authors - Sang Yoon Park ; KO Validated
	WB	J Biol Chem; HIV-1 Vpr enhances proteasomal degradation of MCM10 through the Cul4-DDB1[VprBP] E3 ubiquitin ligase to induce G2/M cell cycle arrest.; Authors - Bizhan Romani
human	WB	J Biol Chem; HIV-1 Vpr Protein Induces Proteasomal Degradation of Chromatin-associated Class I HDACs to Overcome Latent Infection of Macrophages.; Authors - Bizhan Romani