Product Information
67746-1-PBS targets USP14 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Pig, Rabbit samples.
Tested Reactivity | Human, Mouse, Rat, Pig, Rabbit |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | USP14 fusion protein Ag6312 Predict reactive species |
Full Name | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) |
Calculated Molecular Weight | 54 kDa |
Observed Molecular Weight | 60 kDa |
GenBank Accession Number | BC003556 |
Gene Symbol | USP14 |
Gene ID (NCBI) | 9097 |
RRID | AB_2918515 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P54578 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
USP14(Ubiquitin carboxyl-terminal hydrolase 14) is also named as TGT and belongs to the peptidase C19 family. Mammalian USP14 is unique among known UBP enzymes in that it is activated catalytically upon specific association with the 26S proteasome. USP14 inhibition accelerated the degradation of oxidized proteins and enhanced resistance to oxidative stress.