ULBP2 Polyclonal antibody

ULBP2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 31504-1-AP

Synonyms

NKG2DL2, NKG2D ligand 2, N2DL-2, N2DL2, ALCAN-alpha

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Validation Data Gallery

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  WB analysis using 31504-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31504-1-AP (ULBP2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: Jurkat cells, Saos-2 cells

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

31504-1-AP targets ULBP2 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: UL16 binding protein 2
• Calculated Molecular Weight: 27 kDa
• Observed Molecular Weight: 30 kDa
• GenBank Accession Number: NM_025217.4
• Gene Symbol: ULBP2
• Gene ID (NCBI): 80328
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ULBP2, or UL16-binding protein 2, is a member of the retinoic acid early transcript (RAET) family and serves as a ligand for the NKG2D receptor, which is expressed on natural killer (NK) cells, CD8+ T cells, and certain subsets of CD4+ T cells (PMID: 18791713). ULBP2 plays a critical role in the immune response by mediating natural killer cell cytotoxicity and is involved in antigen processing and presentation (PMID: 22102694; 21764762). ULBP2 has been implicated in various cancers and is associated with prognosis and immune infiltration in colon cancer (PMID: 36633827).