UGCGL1 Monoclonal antibody, PBS Only

UGCGL1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3E8G10

Cat no : 68462-1-PBS

Synonyms

FLJ23671, FLJ23796, GT, HUGT1, UGCGL1, UGGT, UGGT1, UGT1, UGTR

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Validation Data Gallery

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  WB analysis using 68462-1-Ig (same clone as 68462-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68462-1-Ig (UGCGL1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68462-1-PBS in a different storage buffer formulation.

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Product Information

68462-1-PBS targets UGCGL1 in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG2b
• Class: Monoclonal
• Type: Antibody
• Immunogen: UGCGL1 fusion protein Ag5940
• Full Name: UDP-glucose ceramide glucosyltransferase-like 1
• Calculated Molecular Weight: 1531 aa, 175 kDa
• Observed Molecular Weight: 170 kDa
• GenBank Accession Number: BC041098
• Gene Symbol: UGCGL1
• Gene ID (NCBI): 56886
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

UDP-glucose:glycoprotein glucosyltransferase 1 (UGCGL1) is a central quality control gatekeeper in the mammalian endoplasmic reticulum (ER) and serves as a folding sensor in the calnexin/calreticulin glycoprotein quality control cycle (PMID: 28425917). UGCGL1 acts as a checkpoint in the quality control of the MHC class I antigen presentation pathway (PMID: 21383159). Western blot analysis detected UGCGL1 at an apparent molecular mass of 170 kDa.