UCH-L1/PGP9.5 Recombinant antibody, PBS Only
UCH-L1/PGP9.5 Uni-rAbTM Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IHC, IF-P, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
241107B2
Cat no : 84154-4-PBS
Synonyms
Validation Data Gallery
Product Information
The immunogen of 84154-4-PBS is UCH-L1/PGP9.5 Fusion Protein expressed in E. coli.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | UCH-L1/PGP9.5 fusion protein Ag6490 |
Full Name | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
Calculated Molecular Weight | 25 kDa |
Observed Molecular Weight | 27 kDa |
GenBank Accession Number | BC000332 |
Gene Symbol | UCHL1 |
Gene ID (NCBI) | 7345 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm (PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene (PMID:15048890).