UBP1 Monoclonal antibody, PBS Only

UBP1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1B10H3

Cat no : 67318-1-PBS

Synonyms

DKFZp686L1745, LBP 1a, LBP 1B, LBP1, LBP1A, LBP1B, Transcription factor LBP 1, UBP1, Upstream binding protein 1

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Validation Data Gallery

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  WB analysis using 67318-1-Ig (same clone as 67318-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67318-1-Ig (UBP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67318-1-PBS in a different storage buffer formulation.

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Product Information

67318-1-PBS targets UBP1 in WB, Indirect ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: UBP1 fusion protein Ag5010
• Full Name: upstream binding protein 1 (LBP-1a)
• Calculated Molecular Weight: 60 kDa
• Observed Molecular Weight: 65-68 kDa
• GenBank Accession Number: BC047235
• Gene Symbol: UBP1
• Gene ID (NCBI): 7342
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

UBP1, also known as Transcription factor LBP-1, is a 540 amino acid protein, which is expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines. UBP1 localizes in nuclear and can be induced by HIV-1 infection of lymphocytes. UBP1 functions as a transcriptional activator in a promoter context-dependent manner and modulates the placental expression of CYP11A1. UBP1 is involved in regulation of the alpha-globin gene in erythroid cells and represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.