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TWEAKR/CD266 Recombinant antibody, PBS Only (Detector)

TWEAKR/CD266 Uni-rAbTM Recombinant Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240991C5

Cat no : 83916-2-PBS

Synonyms

CD266, TNFRSF12A, TweakR, FGF inducible 14, DR3LG

Validation Data Gallery

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  • Cytometric bead array standard curve of MP00861-1

    Cytometric bead array standard curve of MP00861-1

    Cytometric bead array standard curve of MP00861-1, TWEAKR Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83916-1-PBS. Detection antibody: 83916-2-PBS. Standard: Ag13823. Range: 0.78-100 ng/mL.

Product Information

83916-2-PBS targets TWEAKR/CD266 as part of a matched antibody pair:

MP00861-1: 83916-1-PBS capture and 83916-2-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen TWEAKR/CD266 fusion protein Ag13823
Full Name tumor necrosis factor receptor superfamily, member 12A
Calculated Molecular Weight 129 aa, 14 kDa
GenBank Accession NumberBC002718
Gene Symbol TWEAKR
Gene ID (NCBI) 51330
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

TWEAKR (also known as CD266, FN14, TNFRSF12A) is a member of the TNF receptor superfamily which is activated by its ligand, the cytokine TWEAK (TNFSF12). TWEAKR is the smallest member of the TNFR superfamily. TweakR was first described as an FGF-inducible gene that played a role in fibroblast adhesion and migration. Subsequently, the induction of TweakR expression by other growth factors and/or upon tissue injury was observed in multiple cell types, including hepatocytes, endothelial cells, adipocytes, and cardiomyocytes. (PMID: 23073510, PMID: 24409185)