|Positive WB detected in||Jurkat cells, HeLa cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Sample-dependent, check data in validation data gallery|
15719-1-AP targets TUBGCP3 in WB, IF, ELISA applications and shows reactivity with human samples.
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||TUBGCP3 fusion protein Ag8437|
|Full Name||tubulin, gamma complex associated protein 3|
|Calculated molecular weight||103.5 kDa|
|Observed molecular weight||95-101 kDa|
|GenBank accession number||BC007763|
|Gene ID (NCBI)||10426|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
TUBGCP3, also named as γ‐tubulin complex protein 3, localized to the centrosome, is a member of γ-tubulin complex proteins which play key roles in microtubule nucleation and organization. It has been reported that TUBGCP3 rotation can bring γ-tubulin molecules into proximity. 15719-1-AP antibody detects the isoform proteins around 95-101 kDa and 50 kDa in SDS-PAGE.
Nat Cell Biol
The dynamics of microtubule minus ends in the human mitotic spindle.
Modular assembly of the principal microtubule nucleator γ-TuRC.
Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity.
J Cell Sci
MZT1 regulates microtubule nucleation by linking γTuRC assembly to adapter-mediated targeting and activation.
J Cell Sci
Retromer/WASH dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50.
J Neuropathol Exp Neurol
Overexpression and Nucleolar Localization of γ-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma.