TSPO/PBR Polyclonal antibody, PBS Only
TSPO/PBR Polyclonal Antibody for WB, IHC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, IHC, Indirect ELISA
Conjugate
Unconjugated
Cat no : 15444-1-PBS
Synonyms
Validation Data Gallery
Product Information
15444-1-PBS targets TSPO/PBR in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | TSPO/PBR fusion protein Ag7475 |
Full Name | translocator protein (18kDa) |
Calculated Molecular Weight | 18 kDa |
Observed Molecular Weight | 18 kDa |
GenBank Accession Number | BC001110 |
Gene Symbol | TSPO |
Gene ID (NCBI) | 706 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
TSPO, also named Peripheral-type benzodiazepine receptor (PBR), encodes the translocator protein, belonging to tryptophan-rich sensory protein family. The protein is mainly localized in the outer mitochondrial membrane and expressed in steroid-synthesizing tissues (PMID:32881658, PMID:1326278). TSPO is involved in the translocation of cholesterol from the outer to inner mitochondrial membrane (PMID:21119734). In response to injury, TSPO has a upregulated expression in the peripheral nervous system (PMID:32423330, PMID:23251719). TSPO is also as a biomarker in a non-invasive procedure including detecting the inflammation in the heart and atherosclerotic plaques (PMID:24402571).