TRIT1 Polyclonal antibody, PBS Only

• 

  WB analysis using 17141-1-AP (same clone as 17141-1-PBS)

  mouse placenta tissue were subjected to SDS PAGE followed by western blot with 17141-1-AP (TRIT1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17141-1-PBS in a different storage buffer formulation.

TRIT1 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 17141-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

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Product Information

17141-1-PBS targets TRIT1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: TRIT1 fusion protein Ag10906
• Full Name: tRNA isopentenyltransferase 1
• Calculated Molecular Weight: 467 aa, 53 kDa
• Observed Molecular Weight: 53-60 kDa
• GenBank Accession Number: BC107569
• Gene Symbol: TRIT1
• Gene ID (NCBI): 54802
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H3H1
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

IPTases (TRIT1) belong to a group of enzymes that modify both cytoplasmic and mitochondrial tRNAs of eukaryotic cells. Pathogenic mutations to human IPTase (TRIT1) cause mitochondrial insufficiency and neurodevelopmental disease, principally due to decreased modification of the mt-tRNA substrates.(PMID: 32324744, PMID: 36049610)