TRIML2 Polyclonal antibody

• 

  WB analysis using 31976-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31976-1-AP (TRIML2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

TRIML2 Polyclonal Antibody for WB, ELISA

Cat No. 31976-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

Tripartite motif family-like protein 2, SPRYD6, SPRY domain-containing protein 6, RING-type E3 ubiquitin transferase TRIML2, Probable E3 ubiquitin-protein ligase TRIML2

---

Tested Applications

• Positive WB detected in: U2OS cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

31976-1-AP targets TRIML2 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: TRIML2 fusion protein Ag37106
• Full Name: tripartite motif family-like 2
• Calculated Molecular Weight: 50 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC111959
• Gene Symbol: TRIML2
• Gene ID (NCBI): 205860
• RRID: AB_3670164
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q8N7C3
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Tripartite motif family like 2 (TRIML2, also known as SPRYD6) is a member of the tripartite motif (TRIM) family of proteins. It probably interacts with p53 to facilitate the modification of p53 with small ubiquitin-like modifier 2 (SUMO2) (PMID: 25256710). By regulating p53, TRIML2 may also be an important factor in the pathogenesis of Alzheimer's disease (PMID: 27471163).