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TRIM26 Recombinant antibody, PBS Only

TRIM26 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242154B5

Cat no : 84661-4-PBS

Synonyms

ZNF173, Tripartite motif-containing protein 26, TRIM, RNF95, EC:2.3.2.27

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using TRIM26 Recombinant antibody (84661-4-RR)

    WB analysis using 84661-4-RR (same clone as 84661-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84661-4-RR (TRIM26 antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84661-4-PBS in a different storage buffer formulation.

Product Information

84661-4-PBS targets TRIM26 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen TRIM26 fusion protein Ag25546
Full Name tripartite motif-containing 26
Calculated Molecular Weight 62 kDa
Observed Molecular Weight 60-70 kDa
GenBank Accession NumberBC024039
Gene Symbol TRIM26
Gene ID (NCBI) 7726
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation. (PMID: 25763818, PMID: 26611359)