TREM-1/CD354 Polyclonal antibody

TREM-1/CD354 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 30496-1-AP

Synonyms

TREM1, TREM 1, CD354

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Validation Data Gallery

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  WB analysis using 30496-1-AP

  THP-1 cells were subjected to SDS PAGE followed by western blot with 30496-1-AP (TREM1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: THP-1 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

30496-1-AP targets TREM-1/CD354 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: TREM-1/CD354 fusion protein Ag32967
• Full Name: triggering receptor expressed on myeloid cells 1
• Calculated Molecular Weight: 234 aa, 26 kDa
• Observed Molecular Weight: 30 kDa
• GenBank Accession Number: BC017773
• Gene Symbol: TREM1
• Gene ID (NCBI): 54210
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Triggering receptor expressed on myeloid cells 1 (TREM1, also known as CD354) is a member of the immunoglobulin superfamily, which is expressed on neutrophils and monocytes. TREM1 plays a role in the innate immune system. TREM1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers.