Anti-Human TREM-1/CD354 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of human peripheral blood leukocytes using 98154-1-RR (same clone as 98154-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human TREM-1/CD354 Rabbit Recombinant Antibody (98154-1-RR, Clone: 241279D10) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD16. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98154-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98154-1-RR (same clone as 98154-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human TREM-1/CD354 Rabbit Recombinant Antibody (98154-1-RR, Clone: 241279D10)(red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98154-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98154-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98154-1-RR against Human TREM-1/CD354 were performed. The affinity constant is 0.676 nM.

TREM-1/CD354 Uni-rAb^TM Recombinant Antibody for FC

Cat No. 98154-1-PBS

Clone No.241279D10

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

TREM1, TREM 1, CD354, 241279D10

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Product Information

98154-1-PBS targets TREM-1/CD354 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Fusion Protein
• Full Name: triggering receptor expressed on myeloid cells 1
• Calculated Molecular Weight: 26kDa
• GenBank Accession Number: NM_018643.5
• Gene Symbol: TREM1
• Gene ID (NCBI): 54210
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q9NP99-1
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Triggering receptor expressed on myeloid cells 1 (TREM-1, also known as CD354) is a member of the immunoglobulin superfamily, which is expressed on neutrophils and monocytes. TREM1 plays a role in the innate immune system. TREM1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers.