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TRAF6 Monoclonal antibody, PBS Only

TRAF6 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 66498-1-PBS
Clone No.1D1E1

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

RNF85, RING-type E3 ubiquitin transferase TRAF6, Interleukin-1 signal transducer, EC:2.3.2.27, E3 ubiquitin-protein ligase TRAF6

Formulation:  PBS Only
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66498-1-PBS targets TRAF6 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen TRAF6 fusion protein Ag24696 Predict reactive species
Full Name TNF receptor-associated factor 6
Calculated Molecular Weight 522 aa, 60 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC031052
Gene Symbol TRAF6
Gene ID (NCBI) 7189
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9Y4K3
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF6 is recognized as a signal transducer, which activates the NF-κB pathway in response to pro-inflammatory cytokines. TRAF6 has E3 ligase activity and is responsible for inducing Lys-63 (K63)-linked poly-ubiquitination chains, functioning together with E2 Ubc13/Uev1A complex to mediate IKK activation TRAF6 plays a crucial role in the regulation of the innate and adaptive immune responses.

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