Product Information
67244-1-PBS targets TPM4 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with rabbit, pig, rat, mouse, human samples.
Tested Reactivity | rabbit, pig, rat, mouse, human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | TPM4 fusion protein Ag6947 Predict reactive species |
Full Name | tropomyosin 4 |
Calculated Molecular Weight | 248 aa, 29 kDa |
Observed Molecular Weight | 32-35 kDa |
GenBank Accession Number | BC037576 |
Gene Symbol | TPM4 |
Gene ID (NCBI) | 7171 |
ENSEMBL Gene ID | ENSG00000167460 |
RRID | AB_2882523 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P67936 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
TPM4 is a member of tropomyosins (TPMs), a multi-gene family of actin-binding proteins present in all eukaryotic cells. In muscle, TPMs are responsible for mediating contraction via regulation of the actin-myosin interaction. As to non-muscle cells, its proposed role is to stabilize the actin filaments by modulating the interaction with proteins that are responsible for the regulation of actin dynamics. The form of TPM4 in muscle has a higher molecular weight than the form found in non-muscle cells.