TOP2A Recombinant antibody, PBS Only

TOP2A Uni-rAbTM Recombinant Antibody for WB, IF/ICC, IP, Indirect ELISA
Cat No. 82738-4-PBS
Clone No.1J18

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, IP, Indirect ELISA

TOP2, TOP II, EC:5.6.2.2, DNA topoisomerase 2-alpha, DNA topoisomerase 2 alpha

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

82738-4-PBS targets TOP2A in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen TOP2A fusion protein Ag19551 Predict reactive species
Full Name topoisomerase (DNA) II alpha 170kDa
Calculated Molecular Weight 1531 aa, 174 kDa
Observed Molecular Weight~170 kDa
GenBank Accession NumberBC140791
Gene Symbol TOP2A
Gene ID (NCBI) 7153
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP11388
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

TOP2A, also named as TOP2, belongs to the type II topoisomerase family. Topoisomerase II makes double-strand breaks. TOP2 control the topological states of DNA by transient breakage and subsequent rejoining of DNA strands. TOP2A may play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. DNA topoisomerase IIa (170 kDa, TOP2a/170) is essential in proliferating cells by resolving DNA topological entanglements during chromosome condensation, replication, and segregation.

Loading...