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TOP2A Monoclonal antibody, PBS Only

TOP2A Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66541-1-PBS
Clone No.1E12B3

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, IHC, IF/ICC, Indirect ELISA

DNA topoisomerase 2 alpha, TOP2, TOP2A, TP2A

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66541-1-PBS targets TOP2A in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen TOP2A fusion protein Ag19551 Predict reactive species
Full Name topoisomerase (DNA) II alpha 170kDa
Calculated Molecular Weight 1531 aa, 174 kDa
Observed Molecular Weight 174 kDa
GenBank Accession NumberBC140791
Gene Symbol TOP2A
Gene ID (NCBI) 7153
RRIDAB_2881903
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP11388
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

TOP2A, also named as TOP2, belongs to the type II topoisomerase family. Topoisomerase II makes double-strand breaks. TOP2 control the topological states of DNA by transient breakage and subsequent rejoining of DNA strands. TOP2A may play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. DNA topoisomerase IIa (170 kDa, TOP2a/170) is essential in proliferating cells by resolving DNA topological entanglements during chromosome condensation, replication, and segregation.

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