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DR3 Polyclonal antibody

DR3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 55397-1-AP

Synonyms

APO 3, APO3, DDR3, Death receptor 3, DR3, LARD, Protein WSL, Protein WSL 1, TNFRSF12, TNFRSF25, TR3, TRAMP, WSL, WSL 1, WSL LR, WSL1



Tested Applications

Positive WB detected inPC-3 cells, mouse spleen tissue, mouse thymus tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 3 publications below

Product Information

55397-1-AP targets DR3 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name tumor necrosis factor receptor superfamily, member 25
Calculated Molecular Weight 46 kDa
Observed Molecular Weight52 kDa, 17-20 kDa
GenBank Accession NumberNM_003790
Gene Symbol DR3
Gene ID (NCBI) 8718
RRIDAB_11183036
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TNFRSF25, also named as APO3, DDR3, DR3, TNFRSF12, WSL, WSL1, LARD, TRAMP and AIR, is a receptor for TNFSF12/APO3L/TWEAK. TNFRSF25 interacts directly with the adapter TRADD. It mediates activation of NF-kappa-B and induces apoptosis. TNFRSF25 may play a role in regulating lymphocyte homeostasis. It is constitutively and highly expressed by CD4(+)FoxP3(+) Tregs. This antibody can recognize all the isoform of TNFRSF25.

Protocols

Product Specific Protocols
WB protocol for DR3 antibody 55397-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Life Sci

TL1A primed dendritic cells activation exacerbated chronic murine colitis.

Authors - Fei Han
human,mouseWB

Exp Biol Med (Maywood)

Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer

Authors - Wei Wang
mouseWB

J Ethnopharmacol

Transcriptomic analysis reveals the critical role of Chemokine signaling in the anti-atherosclerosis effect of Xuefu Zhuyu Decoction

Authors - Dongdong Jia