TNFAIP3 Monoclonal antibody, PBS Only
TNFAIP3 Monoclonal Antibody for WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat
Applications
WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3A11G6
Cat no : 66695-1-PBS
Synonyms
Validation Data Gallery
Product Information
66695-1-PBS targets TNFAIP3 in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | TNFAIP3 fusion protein Ag18150 |
Full Name | tumor necrosis factor, alpha-induced protein 3 |
Calculated Molecular Weight | 790 aa, 90 kDa |
Observed Molecular Weight | 80 kDa |
GenBank Accession Number | BC114480 |
Gene Symbol | TNFAIP3 |
Gene ID (NCBI) | 7128 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
TNFAIP3, also named A20, is a cytoplasmic zinc finger protein that inhibits nuclear factor kappa-B (NFKB) activity and tumor necrosis factor (TNF)-mediated programmed cell death. A20 is a ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities, and involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity.