TMEM98 Recombinant antibody, PBS Only

TMEM98 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241581A6

Cat no : 84284-5-PBS

Synonyms

UNQ536/PRO1079, Transmembrane protein 98, Protein TADA1, 241581A6

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Validation Data Gallery

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  WB analysis using 84284-5-RR (same clone as 84284-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84284-5-RR (TMEM98 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84284-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84284-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84284-5-RR against Human TMEM98 were performed. The affinity constant is below 1 pM.

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Product Information

The immunogen of 84284-5-PBS is TMEM98 Fusion Protein expressed in E. coli.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: TMEM98 fusion protein Ag6492
• Full Name: transmembrane protein 98
• Calculated Molecular Weight: 25 kDa
• Observed Molecular Weight: 25 kDa
• GenBank Accession Number: BC000526
• Gene Symbol: TMEM98
• Gene ID (NCBI): 26022
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

TMEM98, also named as TADA1, composed of 226 amino acid residues, is a potential single-pass transmembrane protein. It is expression in both nucleus and cytoplasm. TMEM98 was found to be over-expressed in most of the hepatocellular carcinoma tissue. MEM98 is not only a prognostic marker for patients with hepatocellular carcinoma but also a novel molecular target associated with intrinsic and acquired chemoresistance of hepatocellular carcinoma (PMID: 24608572).