TMEM98 Recombinant antibody

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  IF Staining of HepG2 using 84284-4-RR

  Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using TMEM98 antibody (84284-4-RR, Clone: 241581G11 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red).

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  Affinity and Kinetic Characterization of 84284-4-RR

  Biolayer interferometry (BLl) kinetic assays of 84284-4-RR against Human TMEM98 were performed. The affinity constant is 0.974 nM.

TMEM98 Uni-rAb^TM Recombinant Antibody for IF/ICC, ELISA

Cat No. 84284-4-RR

Clone No.241581G11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, ELISA

Synonyms

UNQ536/PRO1079, Transmembrane protein 98, Protein TADA1, 241581G11

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Tested Applications

• Positive IF/ICC detected in: HepG2 cells

Recommended dilution

• Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

84284-4-RR targets TMEM98 in IF/ICC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: TMEM98 fusion protein Ag6492
• Full Name: transmembrane protein 98
• Calculated Molecular Weight: 25 kDa
• GenBank Accession Number: BC000526
• Gene Symbol: TMEM98
• Gene ID (NCBI): 26022
• RRID: AB_3671830
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9Y2Y6
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TMEM98, also named as TADA1, composed of 226 amino acid residues, is a potential single-pass transmembrane protein. It is expression in both nucleus and cytoplasm. TMEM98 was found to be over-expressed in most of the hepatocellular carcinoma tissue. MEM98 is not only a prognostic marker for patients with hepatocellular carcinoma but also a novel molecular target associated with intrinsic and acquired chemoresistance of hepatocellular carcinoma (PMID: 24608572).