TMEM64 Polyclonal antibody, PBS Only

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  WB analysis using 21274-1-AP (same clone as 21274-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21274-1-AP (TMEM64 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21274-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 21274-1-AP (same clone as 21274-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 21274-1-AP (TMEM64 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with . This data was developed using the same antibody clone with 21274-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 21274-1-AP (same clone as 21274-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 21274-1-AP (TMEM64 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with . This data was developed using the same antibody clone with 21274-1-PBS in a different storage buffer formulation.

TMEM64 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 21274-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

21274-1-PBS targets TMEM64 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: TMEM64 fusion protein Ag15753
• Full Name: transmembrane protein 64
• Calculated Molecular Weight: 380 aa, 40 kDa
• Observed Molecular Weight: 40-45 kDa
• GenBank Accession Number: BC113828
• Gene Symbol: TMEM64
• Gene ID (NCBI): 169200
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q6YI46
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Tmem64 (transmembrane protein 64) is a positive modulator of osteoclast differentiation by SERCA2-dependent Ca2+ signaling (PMID: 23395171). Altered Levels of mRNAs for Calcium-Binding/Associated Proteins, Annexin A1, S100A4, and TMEM64 are associated with osteoporosis in peripheral blood mononuclear cells (PMID: 31814858). Tmem64 is involved in the metastatic progression of prostate cancer cells by regulating Wnt3a secretion (PMID: 31289498).