TLR8 Monoclonal antibody, PBS Only
TLR8 Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
WB, IHC, IF-P, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3B6A4
Cat no : 67317-1-PBS
Synonyms
Validation Data Gallery
Product Information
67317-1-PBS targets TLR8 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | TLR8 fusion protein Ag16566 |
Full Name | toll-like receptor 8 |
Calculated Molecular Weight | 1041 aa, 120 kDa |
Observed Molecular Weight | 120 kDa |
GenBank Accession Number | BC101075 |
Gene Symbol | TLR8 |
Gene ID (NCBI) | 51311 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Toll-like receptors (TLRs) are a group of pathogen recognition receptors (PRRs) that can be divided into two subfamilies depending on their subcellular localization(PMID: 32268138). Toll-like receptor 8 (TLR8), a sensor for pathogen-derived single-stranded RNA (ssRNA), binds to uridine (Uri) and ssRNA to induce defense responses (PMID:30535046). TLR8 proteins were expressed in spleen, epididymal sperm, testicular sperm cells, and Leydig cells but were weak in Sertoli cells. It can identify two isoforms,120 and 122 kDa.