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TIPIN Polyclonal antibody, PBS Only

TIPIN Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11972-2-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using TIPIN Polyclonal antibody (11972-2-AP)

    WB analysis using 11972-2-AP (same clone as 11972-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11972-2-AP (TIPIN antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11972-2-PBS in a different storage buffer formulation.

Product Information

11972-2-PBS targets TIPIN in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TIPIN fusion protein Ag2595
Full Name TIMELESS interacting protein
Calculated Molecular Weight 301 aa, 34 kDa
Observed Molecular Weight 48 kDa
GenBank Accession NumberBC000870
Gene Symbol TIPIN
Gene ID (NCBI) 54962
RRIDAB_2205116
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

TIPIN, also named as TIMELESS-interacting protein, is a 301 amino acid protein, which belongs to the CSM3 family. TIPIN Plays an important role in the control of DNA replication and the maintenance of replication fork stability. TIPIN forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. The calculated molecular weight of TIPIN is 34 kDa, but the result of WB is 55-60 kDa, which is similar to the result of publication.(PMID: 24830473)