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THSD7A Polyclonal antibody, PBS Only

THSD7A Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 28524-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using THSD7A Polyclonal antibody (28524-1-AP)

    WB analysis using 28524-1-AP (same clone as 28524-1-PBS)

    mouse kidney tissue was subjected to SDS PAGE followed by western blot with 28524-1-AP (THSD7A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28524-1-PBS in a different storage buffer formulation.

Product Information

28524-1-PBS targets THSD7A in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen THSD7A fusion protein Ag29107
Full Name thrombospondin, type I, domain containing 7A
Calculated Molecular Weight 185 kDa
Observed Molecular Weight240-250 kDa
GenBank Accession NumberNM_015204
Gene Symbol THSD7A
Gene ID (NCBI) 221981
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Thrombospondin type-1 domain-containing protein 7A (THSD7A) is a membrane-associated N-glycoprotein with a molecular weight of 250 kDa, which can be cleaved to release a 210-kDa soluble form (PMID: 22194972; 27214550). THSD7A has a role in angiogenesis. It mediates endothelial cell migration and tube formation (PMID: 2002048). THSD7A has been identified as a second autoantigen involved in adult idiopathic membranous nephropathy in addition to PLA2R1 (PMID: 25394321).