THEM4 Monoclonal antibody

THEM4 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1C12B9

Cat no : 68923-1-Ig

Synonyms

CTMP, EC:3.1.2.2, Carboxyl-terminal modulator protein, Acyl-coenzyme A thioesterase THEM4, Acyl-CoA thioesterase THEM4

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Validation Data Gallery

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  WB analysis using 68923-1-Ig

  Various lysates were subjected to SDS PAGE followed by western blot with 68923-1-Ig (THEM4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: A375 cells, HepG2 cells, HeLa cells, DU 145 cells, LNCaP cells, HEK-293 cells, K-562 cells, TF-1 cells, HL-60 cells

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

68923-1-Ig targets THEM4 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: THEM4 fusion protein Ag6296
• Full Name: thioesterase superfamily member 4
• Calculated Molecular Weight: 27 kDa
• Observed Molecular Weight: 26 kDa
• GenBank Accession Number: BC065277
• Gene Symbol: CTMP
• Gene ID (NCBI): 117145
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

THEM4, which stands for thioesterase superfamily member 4, is a gene in humans that encodes a protein involved in the regulation of the protein kinase B (PKB), also known as Akt pathway. This gene is ubiquitously expressed in various tissues, with notable expression in the kidney and testis. THEM4 can also promote the proliferation of tumor cells by positively regulating Akt activity in breast cancer and nasopharyngeal carcinoma, which presents a contrasting role to its initial characterization.