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TFPI Recombinant antibody, PBS Only (Detector)

TFPI Uni-rAbTM Recombinant Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240977F12

Cat no : 83838-4-PBS

Synonyms

TFI, Lipoprotein-associated coagulation inhibitor, LACI, Extrinsic pathway inhibitor, EPI

Validation Data Gallery

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  • Cytometric bead array standard curve of MP00812-3

    Cytometric bead array standard curve of MP00812-3

    Cytometric bead array standard curve of MP00812-3, TFPI Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83838-1-PBS. Detection antibody: 83838-4-PBS. Standard: Eg0855. Range: 0.781-100 ng/mL.

Product Information

83838-4-PBS targets TFPI as part of a matched antibody pair:

MP00812-3: 83838-1-PBS capture and 83838-4-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Fusion Protein
Full Name tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Calculated Molecular Weight35 kDa
Observed Molecular Weight 40-45 kDa
GenBank Accession NumberNM_006287.6
Gene Symbol TFPI
Gene ID (NCBI) 7035
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Tissue factor pathway inhibitor (TFPI) is a critical anticoagulant protein present in endothelium and platelets. TFPI is produced as two major isoforms in humans, TFPIa and TFPIb that result from alternative splicing. The TFPIb isoform localizes to the endothelium surface where it is a potent inhibitor of tissue factor-factor VIIa complexes that initiate blood coagulation. The TFPIa isoform is present in platelets. TFPI is a Kunitz-type serine protease inhibitor that exerts anticoagulant activity by blocking early procoagulant stimulia. TFPI can enhance anti-thrombotic treatment in sepsis, inflammatory diseases, and cardiovascular diseases.