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TFEC Polyclonal antibody, PBS Only

TFEC Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 29324-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using TFEC Polyclonal antibody (29324-1-AP)

    WB analysis using 29324-1-AP (same clone as 29324-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29324-1-AP (TFEC antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29324-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using TFEC Polyclonal antibody (29324-1-AP)

    WB analysis using 29324-1-AP (same clone as 29324-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29324-1-AP (TFEC antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29324-1-PBS in a different storage buffer formulation.

Product Information

29324-1-PBS targets TFEC in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TFEC fusion protein Ag30973
Full Name transcription factor EC
Calculated Molecular Weight 347 aa, 39 kDa
Observed Molecular Weight37-50 kDa
GenBank Accession NumberBC029891
Gene Symbol TFEC
Gene ID (NCBI) 22797
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The DNA-binding factor TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. TFEC shares a bHLH/LZ structure with TFE3 and a closely related protein microphthalmia-associated transcription factor (MITF), which is critically involved in melanocyte differentiation. The expression of TFEC is mainly in fibroblasts, myoblasts, chondrosarcoma cells and myeloma cells. 50kDa human TFEC isoforms are produced by alternative splicing (PMID: 29303964, PMID: 11467950).