TCF7L1/TCF7L2 Monoclonal antibody, PBS Only

TCF7L1/TCF7L2 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67652-1-PBS
Clone No.2B2D12

Host / Isotype

Mouse / IgG2b

Reactivity

Human, Mouse

Applications

WB, Indirect ELISA

HMG box transcription factor 3, HMG box transcription factor 4, TCF 3, TCF 4, TCF3, TCF4, TCF7L1, TCF7L2, Transcription factor 7 like 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

67652-1-PBS targets TCF7L1/TCF7L2 in WB, Indirect ELISA applications and shows reactivity with Human, Mouse samples.

Tested Reactivity Human, Mouse
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen TCF7L1/TCF7L2 fusion protein Ag28954 Predict reactive species
Full Name transcription factor 7-like 1 (T-cell specific, HMG-box)
Calculated Molecular Weight 63 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC058894
Gene Symbol TCF7L1
Gene ID (NCBI) 83439
RRIDAB_2882851
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9HCS4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

TCF7L1 is one of TCF/LEF transcription factors that are mediators of the Wnt signaling pathway and are antagonized by the TGF-beta signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It's necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. This antibody raised against 1-200aa of human TCF7L1 can also react with TCF7L2.

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