Product Information
67371-1-PBS targets TBXAS1 in Indirect ELISA, IHC, WB applications and shows reactivity with pig, mouse, human samples.
Tested Reactivity | pig, mouse, human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | TBXAS1 fusion protein Ag29177 Predict reactive species |
Full Name | thromboxane A synthase 1 (platelet) |
Calculated Molecular Weight | 60 kDa |
Observed Molecular Weight | 52 kDa |
GenBank Accession Number | BC014117 |
Gene Symbol | TBXAS1 |
Gene ID (NCBI) | 6916 |
RRID | AB_2918487 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P24557 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
TBXAS1 catalyzes the conversion of the prostaglandin endoperoxide into thromboxane A2 as a potent vasoconstrictor and inducer of platelet aggregation.It was identified as novel airway fibroblast-specific markers with integrin-8 (ITGA8) (PMID:20435685). It was observed in the epithelium.It is a monomer with the molecular weight of 60 KDa. It also has two variants with 60.5 kDa and 52.3 kDa (PMID:1730669). It also reavels a molecular weight of 55 kDa in humen uterus (PMID:1386258).