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TAK1 Polyclonal antibody, PBS Only

TAK1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 29167-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using TAK1 Polyclonal antibody (29167-1-AP)

    WB analysis using 29167-1-AP (same clone as 29167-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29167-1-AP (TAK1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29167-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human prostate cancer tissue using TAK1 Polyclonal antibody (29167-1-AP)

    IHC staining of human prostate cancer using 29167-1-AP (same clone as 29167-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 29167-1-AP (TAK1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29167-1-PBS in a different storage buffer formulation.

Product Information

29167-1-PBS targets TAK1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TAK1 fusion protein Ag30725
Full Name mitogen-activated protein kinase kinase kinase 7
Calculated Molecular Weight 579 aa, 64 kDa
Observed Molecular Weight64-70 kDa
GenBank Accession NumberBC017715
Gene Symbol TAK1
Gene ID (NCBI) 6885
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

MAP3K7(Mitogen-activated protein kinase kinase kinase 7) is also named as TAK1 and belongs to the MAP kinase kinase kinase subfamily. It plays an important role in the cascades of cellular responses evoked by changes in the environment. It has been linked to interleukin-1 receptor and tumor necrosis factor receptor signaling (PMID: 16186825). It has 4 isoforms (53-55 kDa, 64-70 kDa and 75-80 kDa) produced by alternative splicing.